49ers edge rusher Mykel Williams could return on Sunday against the Seahawks in a divisional game with numerous storylines. Summary from publisher descriptions · Niner Noise (FanSided)
San Francisco 49ers Headlines
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This season
2026 regular season · completed games only (latest: Week 5)Record4-04 games
Points for1224th of 32
Points against642nd of 32
Point diff+581st of 32
Off. EPA/play ?+.2911st of 32
Def. EPA/play ?+.01718th of 32
Off. success54.5%1st of 32
Def. success45.5%21st of 32
EPA = expected points added per play: how much each snap moved the team's scoring chances. Offense: higher is better. Defense: lower is better. Stats: nflverse (nflfastR), CC BY 4.0 · updated Oct 11, 1:45 PM ET
Trending
Same story = outlets reporting the same development · Related = other anglesSan Francisco 49ers quarterback Brock Purdy put together an impressive third-quarter touchdown drive against the Denver Broncos last week. Summary from publisher descriptions · Yardbarker
1 outlet + 1 relatedKyle Shanahan declares how Dre Greenlaw has energized 49ers
San Francisco 49ers head coach Kyle Shanahan has never hidden his appreciation for Dre Greenlaw. Summary from publisher descriptions · Yardbarker
Niners Nation
SB Nation team blog- 3 keys to a 49ers win over the Seahawks: Is this the Brock Purdy revenge game?
The San Francisco 49ers are taking on the Seattle Seahawks on the road in Week 5, with the winner moving to first in the NFC West. San Francisco has started off the season strong, going 4-0 with several convincing wins.
Read at Niners Nation → - 49ers’ unheralded D-Line is buying them a valuable luxury
The 49ers will get a boost on the defensive line in Week 5, with last year’s first-round pick Mykel Williams primed to make his return against the Seattle Seahawks on Sunday. Williams’ first appearance since tearing his ACL last November in a win over the New York Giants will…
Read at Niners Nation → - NFL game discussion: More London football and a battle of Shanahan DCs
Only one game matters today, but it’s still a busy schedule the rest of the day. We open with another London game, this time featuring the Eagles and Jaguars.
Read at Niners Nation → - 49ers News: Game DAY
Gut check time. Week 5 and it already feels like high-stakes football, this is all I could have ever asked for before the season started.
Read at Niners Nation → - 49ers release veteran defensive lineman after roster moves on Saturday
The San Francisco 49ers got some good news on the injury front this week, as Mykel Williams was activated off the Physically Unable to Perform (PUP) List after a good week of practice. To accommodate Williams, the 49ers made a number of roster moves.
Read at Niners Nation → - Mykel Williams is officially back
The San Francisco 49ers will be getting their 2025 first-round pick back against the Seattle Seahawks on Sunday, as the Niners announced they activated defensive lineman Mykel Williams off the Physically Unable to Perform List ahead of Week 5. Williams, who had been out since…
Read at Niners Nation → Niners Nation: 2 betting previews
- 49ers vs. Seahawks: How to watch, game time, and betting odds
The San Francisco 49ers will be playing their most important game yet this year in Week 5 as they travel to face the Seattle Seahawks. This can be seen as “Part 2” of a test for the 49ers offense going up against respectable defenses.
Read at Niners Nation → - NFL predictions: 49ers and Seahawks feel like a low-scoring game
An early game of the year contender is approaching us here in Week 5, as the San Francisco 49ers are traveling to Lumen Field to take on the Seattle Seahawks in an NFC West showdown. The 49ers have been off to a great start, going 4-0 with wins over the Los Angeles Rams, Miami…
Read at Niners Nation →
- 49ers vs. Seahawks: How to watch, game time, and betting odds
- That one time Kyle Shanahan forgot about Jaxon Smith-Njigba
The San Francisco 49ers are getting ready for Week 5 against the Seattle Seahawks in what is the most important game of the season thus far. If you take the rosters and make a list of the top 10 players between the two of them, Seahawks wide receiver Jaxon Smith-Njigba would…
Read at Niners Nation → - 49ers News: One more sleep until the game of the year (so far)
49ers star DE Nick Bosa eyeing Week 6 return vs. Commanders after calf injury“But the fact that I’m already feeling like I could go out on Monday night and definitely not wait,” Bosa said.
Read at Niners Nation →
Yardbarker
49ers feed- 49ers announce update on George Kittle's game status vs. Seahawks
The San Francisco 49ers provided an update on All-Pro tight end George Kittle's status ahead of today's Week 5 matchup against the Seattle Seahawks at Lumen Field.
Read at Yardbarker → - 49ers’ Brock Purdy Gets Historic News Before Seahawks Game
As the San Francisco 49ers prepare to face the defending Super Bowl champion Seattle Seahawks on Sunday, quarterback Brock Purdy has established himself as one of the most efficient and productive players in the league through the opening weeks of the 2026 season.
Read at Yardbarker → - Former NFL Player Defends Brock Purdy Against Criticism by Claiming Tom Brady & Peyton Manning Were System QBs
In the NFL, no quarterback wants to be dubbed a “system QB”: someone who relies heavily on specific offensive schemes and surrounding talent. But San Francisco 49ers’ Brock Purdy, who was drafted 262nd and was the final pick in the 7th round of the 2022 NFL Draft, has been stuck…
Read at Yardbarker → - 49ers release veteran D-lineman ahead of Seahawks clash
The San Francisco 49ers announced several roster moves on Saturday, a day before their Week 5 matchup against the Seattle Seahawks. However, one move that the team did not announce appeared on the NFL transaction report: the release of veteran defensive lineman Matthew Judon.
Read at Yardbarker → - 49ers Activate DE Mykel Williams To Play In Week 5; Latest On WRs Mike Evans, Christian Kirk
OCTOBER 10: As expected, the 49ers officially announced this afternoon that they have activated Williams from the reserve/physically unable to perform list.
Read at Yardbarker → - 49ers announce roster moves ahead of big game in Seattle, activate Mykel Williams
The San Francisco 49ers announced the following roster moves on Saturday ahead of a big game on Sunday against the Seattle Seahawks. Activated DL Mykel
Read at Yardbarker →
- Kyle Shanahan declares how Dre Greenlaw has energized 49ers
San Francisco 49ers head coach Kyle Shanahan has never hidden his appreciation for Dre Greenlaw. But the linebacker brings something to the defense that goes beyond his ability to make plays.
Read at Yardbarker → - Kyle Shanahan reveals something 49ers QB Brock Purdy must do against Seahawks
San Francisco 49ers quarterback Brock Purdy put together an impressive third-quarter touchdown drive against the Denver Broncos last week. But even with the offense finding the end zone, head coach Kyle Shanahan saw something he wanted his quarterback to clean up.
Read at Yardbarker → - 49ers vs. Seahawks: 5 Players to Watch in Crucial NFC West Clash
The San Francisco 49ers defeated the Denver Broncos 24-14 last Sunday, marking four straight wins. Wide receiver Deebo Samuel and running back Christian McCaffrey each scored.
Read at Yardbarker → - What makes 49ers WR Mike Evans a matchup nightmare for defenses? Kyle Shanahan shares why
San Francisco 49ers wide receiver Mike Evans brings more to the offense than his ability to win contested catches. His size and physicality create problems for defensive backs.
Read at Yardbarker →
San Francisco 49ers official
Official team news- 49ers Announce Roster Moves Ahead of #SFvsSEA
The 49ers have activated DL Mykel Williams, sign DL Ogbo Okoronkwo to the practice squad.
Read at San Francisco 49ers official → - Juszczyk and Three More Ruled OUT vs. Seahawks in Week 5; Williams Questionable Ahead of #SFvsSEA
The San Francisco 49ers released their latest injury updates headed into their contest against the Seattle Seahawks.
Read at San Francisco 49ers official → - 49ers Release DL Ogbo Okoronkwo
The 49ers announced they released DL Ogbo Okoronkwo.
Read at San Francisco 49ers official →
- Morning Report: 49ers Brock Purdy Previews Week 5 Road Matchup Against Seahawks 🗞️
Catch up on the latest San Francisco 49ers headlines, powered by Cisco.
Read at San Francisco 49ers official → - Ways to Watch and Listen: 49ers vs. Seahawks | Week 5
Broadcast and streaming information for the San Francisco 49ers Week 5 matchup against the Seattle Seahawks at Lumen Field.
Read at San Francisco 49ers official → - Morning Report: More Roster Moves as the 49ers Look Ahead to Week 5 🗞️
Catch up on the latest San Francisco 49ers headlines, powered by Cisco.
Read at San Francisco 49ers official → - Ramp and San Francisco 49ers Announce New Multi-Year Partnership
The modern AI automated finance platform and NFL franchise to collaboratively engage and support local Bay Area businesses
Read at San Francisco 49ers official → - 49ers Make Practice Squad Moves
The 49ers announced they have signed WR Xavier Smith to the team’s practice squad and placed WR Dante Pettis on the Practice Squad Injured Reserve List.
Read at San Francisco 49ers official → - Morning Report: Siran Neal Recaps Pivotal Play, 49ers Top Power Rankings After Week 4 🗞️
Catch up on the latest San Francisco 49ers headlines, powered by Cisco.
Read at San Francisco 49ers official →
Niner Noise (FanSided)
Team blog- Is Mykel Williams making his season debut? Latest 49ers injury news and matchups
49ers edge rusher Mykel Williams could return on Sunday against the Seahawks in a divisional game with numerous storylines.
Read at Niner Noise (FanSided) → - 49ers' defense forced Sean Payton to reassert control over Broncos offense
The San Francisco 49ers shut down the Denver Broncos so bad that Sean Payton had to take over play calling duties, which should only give them more confidence.
Read at Niner Noise (FanSided) → - Deebo Samuel is 49ers' not-so-secret weapon they didn't have last time vs. Seahawks
The San Francisco 49ers are looking to avoid a repeat of their last game on the road against the Seahawks, and they need Deebo Samuel to step up.
Read at Niner Noise (FanSided) →
- Brock Purdy's worst game of 2026 is still evidence he's deserving of MVP award
Brock Purdy is in the form of his career and a legitimate MVP candidate throughout the first month of the season, and it took one half of the worst game so far to really showcase why he deserves the accolades.
Read at Niner Noise (FanSided) → - 49ers injury report vs. Seahawks includes best-possible Mike Evans news
The 49ers don't have be concerned whether or not Mike Evans will be healthy enough to play in a pivotal Week 5 showdown against the Seahawks.
Read at Niner Noise (FanSided) → - 49ers need only look back to 2023 to not get too cocky over perfect start to season
The 49ers are off to a great start this season, but history has shown that doesn't mean this season will be smooth sailing by any stretch.
Read at Niner Noise (FanSided) → - Kyle Shanahan needs to get the Mike Macdonald-shaped monkey off his back
Seattle Seahawks head coach Mike Macdonald has had the San Francisco 49ers' number in recent years. Kyle Shanahan and Brock Purdy need to change that.
Read at Niner Noise (FanSided) → - 3 reasons why 49ers will beat Seahawks in Week 5 (and 3 reasons they won't)
In a pivotal matchup against the Seattle Seahawks, the 49ers boast certain advantages that could put them over the top.
Read at Niner Noise (FanSided) → - Mykel Williams' return to 49ers will inevitably be Sam Darnold's worst nightmare
49ers edge rusher Mykel Williams is returning just in the nick of time.
Read at Niner Noise (FanSided) →
NBC Sports Bay Area 49ers
Local beat coverage- NFL fines 49ers' Dre Greenlaw nearly $12K for taunting toward Broncos sideline
- 49ers activate Mykel Williams from PUP list to make season debut vs. Seahawks
- Kyle Shanahan explains how 49ers' Mike Evans can ‘stress' tough Seahawks defense
NBC Sports Bay Area 49ers: 2 betting previews (Week 5)
- Rob Gronkowski places Brock Purdy's NFL MVP odds above two powerhouse QBs
- Why Richard Sherman picks 49ers to beat Seahawks in Week 5 NFC West matchup
CHICAGO, ILLINOIS – DECEMBER 26: Richard Sherman looks on from the set of the TNF on Prime pregame show prior to the game between the Seattle Seahawks and the Chicago Bears at Soldier Field on December 26, 2024 in Chicago, Illinois. (Photo by Quinn Harris/Getty Images)
Read at NBC Sports Bay Area 49ers →
- Kyle Shanahan admits 49ers take Kyle Juszczyk for granted amid injury absence
- Five 49ers to watch as Kyle Shanahan, offense try to solve Seahawks in Week 5
SANTA CLARA, CALIFORNIA – OCTOBER 04: Mike Evans #5 of the San Francisco 49ers runs with the ball after a catch against the Denver Broncos in the fourth quarter of an NFL football game at Levi’s Stadium on October 04, 2026 in Santa Clara, California. (Photo by Thearon W.…
Read at NBC Sports Bay Area 49ers → - Why Kyle Shanahan believes ‘aggressive' DC Raheem Morris benefits 49ers' defense
- 49ers QB Brock Purdy reveals how recent losses to Seahawks weighed on him
- 49ers star DE Nick Bosa eyeing Week 6 return vs. Commanders after calf injury
- Mykel Williams to make season debut in 49ers-Seahawks; Upton Stout questionable
Around the NFL
From league outlets- NFL Week 5 odds, predictions, expert picks: Who has edge in 49ers vs. Seahawks?
CBSSports.com and SportsLine break down every single NFL game in Week 5
Read at CBS Sports → - Use FanDuel promo code to get $250 bonus bets by targeting Bears-Packers, 49ers-Seahawks, more NFL Week 5
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Read at CBS Sports → - Use BetMGM bonus code CBSSPORTS to get $1,500 bonus bets for Seahawks-49ers, Ravens-Falcons, NFL Week 5
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Read at CBS Sports → - Best Kalshi promo code CBSSPORTS55 in California: Get $55 bonus for Chargers, 49ers, Rams Week 5 NFL games
Kalshi California users can make trades on the state's three NFL teams for Week 5 and receive a $55 bonus on Sunday
Read at CBS Sports →
- NFL Week 5 preview: 49ers, Purdy look to solve Seahawks defence
The 49ers and Brock Purdy have looked nearly unstoppable this season, but now they face the ultimate test against the vaunted Seahawks defence. Kellen Forrest previews the big NFC West clash and much more in his Week 5 preview.
Read at Sportsnet → - Can the Seahawks' defense again silence the 49ers' hot offense Sunday?
Seattle's defense stole the show the past two times these teams met. But the 49ers and Brock Purdy are on a roll heading into Week 5.
Read at ESPN → - 49ers DE Mykel Williams to make season debut vs. Seahawks
49ers defensive end Mykel Williams will make his 2026 debut Sunday against the Seahawks, a little less than a year after tearing his ACL and suffering meniscus damage in his right knee.
Read at ESPN → - NFL rescinds fine against 49ers’ Kyle Juszczyk for chug celebration
San Francisco 49ers fullback Kyle Juszczyk won his appeal over the fines issued by the NFL for what it deemed an “offensive” celebration when he imitated drinking a beverage, which the league said looked like he was chugging a beer.
Read at Sportsnet →