San Francisco 49ers Headlines

The San Francisco 49ers are taking on the Seattle Seahawks on the road in Week 5, with the winner moving to first in the NFC West. San Francisco has started off the season strong, going 4-0 with several convincing wins.

The 49ers will get a boost on the defensive line in Week 5, with last year’s first-round pick Mykel Williams primed to make his return against the Seattle Seahawks on Sunday. Williams’ first appearance since tearing his ACL last November in a win over the New York Giants will…

Only one game matters today, but it’s still a busy schedule the rest of the day. We open with another London game, this time featuring the Eagles and Jaguars.

Gut check time. Week 5 and it already feels like high-stakes football, this is all I could have ever asked for before the season started.

The San Francisco 49ers got some good news on the injury front this week, as Mykel Williams was activated off the Physically Unable to Perform (PUP) List after a good week of practice. To accommodate Williams, the 49ers made a number of roster moves.

The San Francisco 49ers will be getting their 2025 first-round pick back against the Seattle Seahawks on Sunday, as the Niners announced they activated defensive lineman Mykel Williams off the Physically Unable to Perform List ahead of Week 5. Williams, who had been out since…

The San Francisco 49ers have released the list of inactive players for their Week 5 matchup against the Seattle Seahawks. These seven players will not suit up for the game.

The San Francisco 49ers provided an update on All-Pro tight end George Kittle's status ahead of today's Week 5 matchup against the Seattle Seahawks at Lumen Field.

As the San Francisco 49ers prepare to face the defending Super Bowl champion Seattle Seahawks on Sunday, quarterback Brock Purdy has established himself as one of the most efficient and productive players in the league through the opening weeks of the 2026 season.

In the NFL, no quarterback wants to be dubbed a “system QB”: someone who relies heavily on specific offensive schemes and surrounding talent. But San Francisco 49ers’ Brock Purdy, who was drafted 262nd and was the final pick in the 7th round of the 2022 NFL Draft, has been stuck…

The San Francisco 49ers announced several roster moves on Saturday, a day before their Week 5 matchup against the Seattle Seahawks. However, one move that the team did not announce appeared on the NFL transaction report: the release of veteran defensive lineman Matthew Judon.

OCTOBER 10: As expected, the 49ers officially announced this afternoon that they have activated Williams from the reserve/physically unable to perform list.

Take a look at players who have been ruled out for the San Francisco 49ers Week 5 matchup versus the Seattle Seahawks.

The 49ers have activated DL Mykel Williams, sign DL Ogbo Okoronkwo to the practice squad.

The San Francisco 49ers released their latest injury updates headed into their contest against the Seattle Seahawks.

Mike Evans' rib injury won't be the only hurdle he will face in the 49ers' Week 5 matchup against the Seahawks.

49ers edge rusher Mykel Williams could return on Sunday against the Seahawks in a divisional game with numerous storylines.

The San Francisco 49ers shut down the Denver Broncos so bad that Sean Payton had to take over play calling duties, which should only give them more confidence.

The 49ers will have tight end George Kittle for today's game against the Seahawks after coming down with an illness.

The 49ers will have tight end George Kittle for today's game against the Seahawks after coming down with an illness.

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